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By Leopold G. Koss and Dulcie V. Coleman (Auth.)

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Jones. New York: John Wiley 16. , RICHART, R. M. a n d TERNER, J. Y. ( 1 9 6 7 ) Deoxyribonucleic acid content of presumed precursors of endometrial carcinoma, Cancer, 20, 2067-2077 17. , WAMTACH, E. v. and WÜRTHNER, κ. (1974) DNA content of normal, hyperplastic and malignant endometrium, determined cytophotometrically, Archiv für Gynäkologie, 217, 349-365 18. FETTIG, o. (1965) 3H-Index-Bestimmungen und -Berechnungen des mittleren Generationszeit (Lebensdauer) der Einzelabschnitte des gesunden und krankhaften Endometriums nach autoradiographischen Untersuchungen mit 3H-Thymidin, Archiv für Gynäkologie, 200, 659-677 19.

M. Wynn. New York: Plenum Press 42 Ultrastructural dynamics of endometrial hyperplasia and neoplasia 33. BOUTSELIS, J. G. (1973) Histochemistry of the normal endometrium. In The Uterus, pp. 175-184. International Academy of Pathology Monograph, vol. 14. Ed. by H. J. Norris, A. T. Hertig and M. R. Abell. Baltimore, Md: Williams & Wilkins 34. , BERTRAND, G. and GELFAND, M. M. (1979) Studies on the cytodynamics of human endometrial regeneration. III. In vitro short term incubation historadioautography, American Journal of Obstetrics and Gynecology, 134, 297-304 35.

The need for early recognition of malignant endometrial disease appears to be becoming increasingly pressing in the light of recent figures from the United States which have shown that the incidence of adenocarcinoma of the endometrium is increasing47. This is thought to be due at least in part to the increasing use of exogenous oestrogen in gynaecological 58 The value of endometrial aspiration in gynaecological practice practice in the United States, as the number of cases of endometrial cancer in the UK, where the administration of oestrogen therapy is limited, has not shown the same marked rise4.

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